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Immunisation schedule South Africa: the free vaccines and when they are due

The EPI-SA schedule covers birth to 12 years at no cost in public clinics, and a missed dose never means starting again.

Ezra Labuschagne by Ezra Labuschagne
14 September 2026, 08:56
in News
A nurse at a South African public clinic giving a baby a vaccination while the mother holds the Road to Health booklet

Every vaccine on the immunisation schedule South Africa uses in its public clinics is free, from the two shots given at birth to the booster at 12 years. No medical aid, no appointment and no fee. The schedule is set by the Expanded Programme on Immunisation, EPI-SA, and was last revised in 2024, when the measles vaccine at 6 and 12 months was replaced with a combined measles and rubella shot.

The reminder is timely. Gauteng’s health department said on 7 September 2026 that immunisation coverage in the first quarter of the 2026/27 financial year sat at 72% for children under one year, against a national target of 90%, and 70.7% for the second dose of the measles and rubella vaccine. Tshwane was the weakest district at 59.2%, followed by Sedibeng at 69.5%. West Rand was the strongest at 90.6%.

The routine schedule

Age Vaccines
Birth BCG, oral polio (OPV-0)
6 weeks OPV-1, rotavirus 1, pneumococcal 1, hexavalent 1
10 weeks Hexavalent 2
14 weeks Rotavirus 2, pneumococcal 2, hexavalent 3
6 months Measles and rubella 1
9 months Pneumococcal 3
12 months Measles and rubella 2
18 months Hexavalent 4
6 years Tdap 1
12 years Tdap 2

The hexavalent shot covers six diseases in one injection: diphtheria, tetanus, pertussis, polio, hepatitis B and Haemophilus influenzae type b. Tdap covers tetanus, diphtheria and pertussis.

Two campaign-based vaccinations sit outside the clinic visits. Tdap is given to Grade 5 learners, and the human papillomavirus vaccine is given in two doses to girls aged 9 and older, also in schools.

Three rules from the national schedule that parents ask about:

  • The hepatitis B birth dose is given only to babies whose mothers tested positive for HBsAg during pregnancy.
  • Rotavirus vaccine is not given after 24 weeks. If you miss that window, the dose is gone, but the rest of the schedule carries on normally.
  • The measles and rubella dose given between 6 months and 9 months must not be given with any other vaccine on the same day. From 9 months it can be combined with others.

If your child has missed doses

A missed dose does not mean starting the series again. The clinic picks up from where the record stops, and previous doses stay valid no matter how long ago they were given. The national catch-up schedule sets upper age limits for each vaccine:

Vaccine Catch-up limit
BCG 12 months
Oral polio birth dose 6 months
Hexavalent 59 months
Rotavirus 24 weeks
Pneumococcal 72 months
Tdap 15 years
Measles and rubella No upper age limit

Take the Road to Health booklet with you. If it has been lost, go anyway. The national department’s guidance is that health workers must assist and give catch-up doses where needed rather than turn a child away. Clinics are also expected to check missed doses whenever a child up to 12 years old presents for any reason, including curative visits, hospital admissions and school health visits.

Most clinics vaccinate in the morning, so go early.

Why the numbers matter

The department counts a child who has not had the first hexavalent dose as a zero-dose child. In the 2023/24 financial year the districts with the highest proportions of zero-dose children were O.R. Tambo and Alfred Nzo in the Eastern Cape, at 41% and 40%, and Bojanala in North West and Harry Gwala in KwaZulu-Natal, both at 34%. By number, the biggest gaps were in Johannesburg, eThekwini and Ekurhuleni.

Measles spreads faster than almost any other infection, and the national target for measles coverage is 95%, higher than the 90% target for general under-one coverage, precisely because gaps in a community are enough to let an outbreak start.

Watch for these symptoms

Gauteng’s health department asked parents of unvaccinated or partly vaccinated children to watch for fever, rash, a persistent cough, muscle weakness, neck stiffness, jaundice, severe headache or seizures, and to take the child to a clinic rather than wait.

What it costs outside the state system

The same vaccines are available from private doctors and pharmacies, at a price. Private schedules also carry vaccines outside the state programme, including chickenpox, hepatitis A and the combined measles, mumps and rubella shot. Medical schemes usually pay childhood vaccinations from a preventive care benefit rather than from savings, but that varies by plan, and scheme contributions rise every year, as set out in the medical aid price increases.

Clinics ask for identity documents when they open a file for a child. If the birth has not been registered yet, see how to get an unabridged birth certificate. Families using clinic services for a young child may also qualify for the SASSA child support grant.

Where to check

The Expanded Programme on Immunisation schedule, the vaccinator’s manual and the catch-up tables are published by the National Department of Health on its knowledge hub at knowledgehub.health.gov.za. Your nearest clinic can confirm which doses are outstanding from the Road to Health booklet.

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Source: National Department of Health
Tags: child healthDepartment of HealthGautengGovernment Servicesimmunisation
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Ezra Labuschagne

Ezra Labuschagne

Ezra Labuschagne is the founder, editor, and publisher of Southafriworld, an independent South African digital news publication. Based in Pretoria, South Africa, he leads the publication’s editorial direction, publishing standards, content review, and audience strategy. His work focuses on current affairs, public interest reporting, business, the economy, public policy, and major developments that affect daily life in South Africa. As founder and editor, he is responsible for final editorial oversight, including source review, accuracy, updates, corrections, and publishing standards across Southafriworld.

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